PROMER

PROMER™

PROMER tech is composed of DNA-RNA-DNA structure and performs primer and probe functions simultaneously.

ADVANTAGES

SIMPLICITY

PROMER performs both functions of primer and probe in a single nucleic acid. As a result, PROMER requires smaller amount of oligos, reduces dimer formation, and  is more cost-effective. 

SELECTIVE AMPLIFICATION

PROMER initiates extension only when the RNA site perfectly matches the target sequence. This feature prevents non-specific extension, and ensures superior performance in point mutation detection.

ERROR CORRECTION

RNA site in PROMER is denatured from the template when extended. It enables error corrected amplification even in case of non-specific extension, so called template dependent amplification.

LOW SPATIAL LIMITATION

PROMER is a single nucleotide, unlike conventional methods consisting of primer and probe. PROMER is more adaptable to small amplicons such as micro RNA due to its lower spatial limitation.